The Center for Pharmaceutical Development (CPD) focuses on novel approaches to the final three stages of new drug development: active pharmaceutical ingredients manufacturing; drug product formulation; and analytical methods. CPD's mission is to create more selective and robust biological and chemical catalysts; develop methods for stabilizing drugs and vaccines; and design new techniques for nondestructive evaluation of pharmaceutical products.
CPD researches the creation of robust biological and chemical catalysts with better selectivity that will allow for more streamlined processes (manufacturing); the development of improved methods for stabilizing pharmaceuticals to protect the nation's drug supply (formulation); and the design of new analytical techniques for the nondestructive, accurate, and rapid evaluation of pharmaceutical products.
Representative research areas include:
More selective and robust processes with less environmental footprint
Novel and improved existing biocatalysts, such as redox biocatalysts and hydrolases, from beta-lactam hydrolases to semisynthetic beta-lactams.
Integrated reaction-separation schemes
Integration of reaction and product/(bio) catalyst separation, with the goal of rapidly scalable, robust, and thus economical processes.
Methods to ensure long-term stability of tablets, proteins, and vaccines