Center for Bioanalytic Metrology (CBM)
The Center for Bioanalytic Metrology (CBM) advances U.S. competitiveness by working with industry to solve current, emerging, and industry-relevant challenges in measurement science and technology. The CBM has two overarching objectives: to deliver best-in-class molecular measurement tools and expertise that enable the development of powerful new technologies and capabilities across the pharmaceutical, biotechnology, nutrition and agriculture, energy, and analytical instrumentation sectors; and to serve as a proving ground for applications of new instrumentation to cutting-edge chemical and biochemical problems.
Measurement science, and associated instrumentation, is a key contributor to the U.S. economy, enabling advances in everything from drug discovery to materials manufacturing. By bringing together companies in these high-technology sectors with major analytical instrument makers, CBM bridges the gap between the initial demonstration of new ideas — the traditional province of academia — and the delivery of practical technologies.
- Indiana University
- University of Notre Dame
- Purdue University
CBM provides its members with research solutions in a variety of areas, including:
- Analysis of rare or extremely dilute cells, molecules, exosomes, etc.
- Artificial intelligence-driven instrumentation, feedback optimization, and "driverless" instruments.
- Discrimination between large biomolecules and their multimolecule complexes.
- Enhanced imaging of cells, organisms, and chemical processes.
- Massively parallel approaches to chemical cytometry, genetic profiling, and panel screening.
- Online and nearline in situ measurements.
- Point-of-use analysis, companion diagnostics, and inexpensive testing in the field.
- Reduced volume/materials analysis and experimentation at high throughput and productivity.
Ultrahigh sensitivity assays for trace-level biomarkers and impurities.